If he does an LS4 swap, there won't be enough from to spit in the engine compartment, much less put a turbo or blower in there.
Hey T-bat, I like RooK's idea of the turbo, but have you considered a remote-mount turbo system? (I know, I'm all about these things lol)
STS has their universal system with pretty much everything you need at about $3k. You'll need some pipe fabrication for the exhaust work and intake plumbing but ZZPs turbo kits run around $3k anyway so it wouldn't be that much more expensive. Plus, you could push more boost due to the pressure loss from the distance, as well as the slight intercooling effect of running though all that pipe.